Regeneration of lost brain tissues by genetic manipulation of nou-darake in Schmidtea mediterranea planarians
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چکیده
منابع مشابه
Neoblast Specialization in Regeneration of the Planarian Schmidtea mediterranea
Planarians can regenerate any missing body part in a process requiring dividing cells called neoblasts. Historically, neoblasts have largely been considered a homogeneous stem cell population. Most studies, however, analyzed neoblasts at the population rather than the single-cell level, leaving the degree of heterogeneity in this population unresolved. We combined RNA sequencing of neoblasts fr...
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Planarians have been used as a model to study development and regeneration for more than 200 years. Research on these animals has traditionally focused on surgical and pharmacological manipulations. Recently, the dissection of planarians has become more molecular in nature. The isolation of thousands of expressed sequence tags and the introduction of in situ hybridizations, immunocytology, and ...
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The planarian Schmidtea mediterranea is rapidly emerging as a model organism for the study of regeneration, tissue homeostasis and stem cell biology. The recent sequencing, assembly and annotation of its genome are expected to further buoy the biomedical importance of this organism. In order to make the extensive data associated with the genome sequence accessible to the biomedical and planaria...
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The most prominent and dramatic example of regeneration in vertebrates is the complete reconstitution of amphibian limbs and fish fins by epimorphic regeneration. Research into the molecular regulation of this fascinating biological problem is of high medical interest due to the potential application in replacing old or damaged tissues in humans. Retinoic acid (RA), a small lipophilic molecule ...
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ژورنال
عنوان ژورنال: UC Merced Undergraduate Research Journal
سال: 2014
ISSN: 2373-809X
DOI: 10.5070/m471025002